Composition:
Each film coated tablet contains 40mg Alverine Citrate.
Mechanism of Action:
Spasmorin is a spasmolytic which has a specific action on the smooth muscle of the alimentary tract and uterus، without affecting the heart، blood vessels، and muscle at therapeutic doses.
Indications:
The relief of smooth muscle spasm in conditions such as irritable bowel syndrome. Painful diverticular disease of the colon and primary dysmenorrhoea.
Dosage:
Children: Not recommended.
Adults: 1 - 2 film coated tablets 1 - 3 times daily.
Side - Effects:
It may occur nausea، headache، dizziness، itching، rash، and allergic reactions.
Contra - Indications:
Hypersensitivity to the drug، paralytic، ileuses intestinal obstruction.
Drug - Interactions:
None stated.
Pharmacokinetics:
After oral administration، Spasmorin is rapidly converted to its primary active metabolite، which is then further converted to secondary metabolites. The peak plasma level of the most active metabolite occurs between 1-1.5 hours after oral dosing.
Elimination:
There is a high renal clearance by active renal secretion.
Use in Pregnancy or Lactation:
It’s not recommended to use during pregnancy or lactation.
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